3csl

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3csl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3csl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3csl RCSB], [http://www.ebi.ac.uk/pdbsum/3csl PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3csl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3csl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3csl RCSB], [http://www.ebi.ac.uk/pdbsum/3csl PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/HASA_SERMA HASA_SERMA]] Can bind free heme and also acquire it from hemoglobin. Conveys heme from hemoglobin to the HasR receptor which releases it into the bacterium. HasR alone can take up heme but the synergy between HasA and HasR increases heme uptake 100-fold.<ref>PMID:7937909</ref> <ref>PMID:9171402</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Serratia marcescens]]
[[Category: Serratia marcescens]]
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[[Category: Diederichs, K.]]
+
[[Category: Diederichs, K]]
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[[Category: Krieg, S.]]
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[[Category: Krieg, S]]
[[Category: Beta-barrel]]
[[Category: Beta-barrel]]
[[Category: Heme]]
[[Category: Heme]]

Revision as of 19:55, 25 December 2014

Structure of the Serratia marcescens hemophore receptor HasR in complex with its hemophore HasA and heme

3csl, resolution 2.70Å

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