2w7h
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w7h RCSB], [http://www.ebi.ac.uk/pdbsum/2w7h PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w7h RCSB], [http://www.ebi.ac.uk/pdbsum/2w7h PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q7SIB6_BACST Q7SIB6_BACST]] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051] Interconversion of serine and glycine (By similarity).[RuleBase:RU000585] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Serine hydroxymethyltransferase|Serine hydroxymethyltransferase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Geobacillus stearothermophilus]] | [[Category: Geobacillus stearothermophilus]] | ||
[[Category: Glycine hydroxymethyltransferase]] | [[Category: Glycine hydroxymethyltransferase]] | ||
| - | [[Category: Bhavani, B S | + | [[Category: Bhavani, B S]] |
| - | [[Category: Bisht, S | + | [[Category: Bisht, S]] |
| - | [[Category: Kaul, P | + | [[Category: Kaul, P]] |
| - | [[Category: Murthy, M R.N | + | [[Category: Murthy, M R.N]] |
| - | [[Category: Prakash, V | + | [[Category: Prakash, V]] |
| - | [[Category: Rajaram, V | + | [[Category: Rajaram, V]] |
| - | [[Category: Rao, N Appaji | + | [[Category: Rao, N Appaji]] |
| - | [[Category: Savithri, H S | + | [[Category: Savithri, H S]] |
[[Category: One-carbon metabolism]] | [[Category: One-carbon metabolism]] | ||
[[Category: Plp-dependent enzyme]] | [[Category: Plp-dependent enzyme]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 19:55, 25 December 2014
CRYSTAL STRUCTURE OF Y51FBSSHMT OBTAINED IN THE PRESENCE OF GLY AND 5-FORMYL TETRAHYDROFOLATE
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