2f2s

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[[Image:2f2s.gif|left|200px]]<br /><applet load="2f2s" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2f2s.gif|left|200px]]
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caption="2f2s, resolution 2.00&Aring;" />
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'''Human mitochondrial acetoacetyl-CoA thiolase'''<br />
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{{Structure
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|PDB= 2f2s |SIZE=350|CAPTION= <scene name='initialview01'>2f2s</scene>, resolution 2.00&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=COA:COENZYME A'>COA</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Acetyl-CoA_C-acetyltransferase Acetyl-CoA C-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.9 2.3.1.9]
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|GENE= ACAT1, ACAT, MAT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Human mitochondrial acetoacetyl-CoA thiolase'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2F2S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=COA:'>COA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 2ES8. Active as [http://en.wikipedia.org/wiki/Acetyl-CoA_C-acetyltransferase Acetyl-CoA C-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.9 2.3.1.9] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2S OCA].
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2F2S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 2ES8. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2S OCA].
[[Category: Acetyl-CoA C-acetyltransferase]]
[[Category: Acetyl-CoA C-acetyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: acat1; acetyl-coenzyme a acetyltransferase 1; t2; mat; thil]]
[[Category: acat1; acetyl-coenzyme a acetyltransferase 1; t2; mat; thil]]
[[Category: sgc]]
[[Category: sgc]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:17:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:47:22 2008''

Revision as of 14:47, 20 March 2008

Image:2f2s.gif


PDB ID 2f2s

Drag the structure with the mouse to rotate
, resolution 2.00Å
Ligands: and
Gene: ACAT1, ACAT, MAT (Homo sapiens)
Activity: Acetyl-CoA C-acetyltransferase, with EC number 2.3.1.9
Coordinates: save as pdb, mmCIF, xml



Human mitochondrial acetoacetyl-CoA thiolase


Disease

Known diseases associated with this structure: Alpha-methylacetoacetic aciduria OMIM:[607809], Hypermethioninemia, persistent, autosomal dominant, due to methionine adenosyltransferase I/III deficiency OMIM:[250850], Methionine adenosyltransferase deficiency, autosomal recessive OMIM:[250850]

About this Structure

2F2S is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2ES8. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 16:47:22 2008

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