3rnv

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rnv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rnv RCSB], [http://www.ebi.ac.uk/pdbsum/3rnv PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rnv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rnv RCSB], [http://www.ebi.ac.uk/pdbsum/3rnv PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/POLG_TUMVJ POLG_TUMVJ]] Capsid protein: involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification. Nuclear inclusion protein B: a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Helper component proteinase: required for aphid transmission and also has proteolytic activity. Only cleaves a Gly-Gly dipeptide at its own C-terminus. Interacts with virions and aphid stylets. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. May have RNA-binding activity (By similarity). Cytoplasmic inclusion protein: has helicase activity. It may be involved in replication (By similarity). Both 6K peptides are indispensable for virus replication (By similarity). Nuclear inclusion protein A: has RNA-binding and proteolytic activities.
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</StructureSection>
</StructureSection>

Revision as of 20:00, 25 December 2014

Structure of the autocatalytic cysteine protease domain of potyvirus helper-component proteinase

3rnv, resolution 2.00Å

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