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2aq2

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2aq2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AQ2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2aq2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AQ2 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2apb|2apb]], [[2apf|2apf]], [[2apt|2apt]], [[2apv|2apv]], [[2apw|2apw]], [[2apx|2apx]], [[2aq1|2aq1]], [[2aq3|2aq3]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2apb|2apb]], [[2apf|2apf]], [[2apt|2apt]], [[2apv|2apv]], [[2apw|2apw]], [[2apx|2apx]], [[2aq1|2aq1]], [[2aq3|2aq3]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">entC3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">entC3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aq2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aq2 RCSB], [http://www.ebi.ac.uk/pdbsum/2aq2 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aq2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aq2 RCSB], [http://www.ebi.ac.uk/pdbsum/2aq2 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ENTC3_STAAU ENTC3_STAAU]] Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Cho, S.]]
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[[Category: Cho, S]]
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[[Category: Guan, R.]]
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[[Category: Guan, R]]
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[[Category: Kerzic, M C.]]
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[[Category: Kerzic, M C]]
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[[Category: Kieke, M C.]]
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[[Category: Kieke, M C]]
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[[Category: Kranz, D M.]]
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[[Category: Kranz, D M]]
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[[Category: Mariuzza, R A.]]
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[[Category: Mariuzza, R A]]
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[[Category: Sundberg, E J.]]
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[[Category: Sundberg, E J]]
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[[Category: Swaminathan, C P.]]
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[[Category: Swaminathan, C P]]
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[[Category: Yang, J.]]
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[[Category: Yang, J]]
[[Category: Complex structure]]
[[Category: Complex structure]]
[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Staphlococcal enterotoxin c3]]
[[Category: Staphlococcal enterotoxin c3]]
[[Category: T-cell receptor v beta domain]]
[[Category: T-cell receptor v beta domain]]

Revision as of 20:15, 25 December 2014

Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant

2aq2, resolution 1.80Å

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