1pn7
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1pn7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PN7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PN7 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1pn7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PN7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PN7 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gix|1gix]], [[1giy|1giy]], [[1pn6|1pn6]], [[1pn8|1pn8]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gix|1gix]], [[1giy|1giy]], [[1pn6|1pn6]], [[1pn8|1pn8]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pn7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pn7 RCSB], [http://www.ebi.ac.uk/pdbsum/1pn7 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pn7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1pn7 RCSB], [http://www.ebi.ac.uk/pdbsum/1pn7 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RL11_THEMA RL11_THEMA]] This protein binds directly to 23S ribosomal RNA. [[http://www.uniprot.org/uniprot/RS12_THET8 RS12_THET8]] With S4 and S5 plays an important role in translational accuracy (By similarity).[HAMAP-Rule:MF_00403_B] Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.[HAMAP-Rule:MF_00403_B] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Ribosomal protein L11|Ribosomal protein L11]] | ||
*[[Ribosomal protein S12|Ribosomal protein S12]] | *[[Ribosomal protein S12|Ribosomal protein S12]] | ||
== References == | == References == | ||
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[[Category: Thermotoga maritima]] | [[Category: Thermotoga maritima]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
| - | [[Category: Ehrenberg, M | + | [[Category: Ehrenberg, M]] |
| - | [[Category: Frank, J | + | [[Category: Frank, J]] |
| - | [[Category: Rawat, U | + | [[Category: Rawat, U]] |
| - | [[Category: Sengupta, J | + | [[Category: Sengupta, J]] |
| - | [[Category: Valle, M | + | [[Category: Valle, M]] |
| - | [[Category: Zavialov, A | + | [[Category: Zavialov, A]] |
[[Category: Ribosomal protein]] | [[Category: Ribosomal protein]] | ||
[[Category: Rna binding protein-rna complex]] | [[Category: Rna binding protein-rna complex]] | ||
[[Category: Trna]] | [[Category: Trna]] | ||
[[Category: Trna binding protein]] | [[Category: Trna binding protein]] | ||
Revision as of 20:15, 25 December 2014
Coordinates of S12, L11 proteins and P-tRNA, from the 70S X-ray structure aligned to the 70S Cryo-EM map of E.coli ribosome
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