2j5o
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2j5o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J5O FirstGlance]. <br> | <table><tr><td colspan='2'>[[2j5o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J5O FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2iut|2iut]], [[2iuu|2iuu]], [[2j5p|2j5p]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2iut|2iut]], [[2iuu|2iuu]], [[2j5p|2j5p]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j5o RCSB], [http://www.ebi.ac.uk/pdbsum/2j5o PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j5o RCSB], [http://www.ebi.ac.uk/pdbsum/2j5o PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FTSK_PSEAE FTSK_PSEAE]] Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (Probable).<ref>PMID:16916635</ref> <ref>PMID:18722176</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
| - | [[Category: Allen, M D | + | [[Category: Allen, M D]] |
| - | [[Category: Arciszewska, L | + | [[Category: Arciszewska, L]] |
| - | [[Category: Baker, R | + | [[Category: Baker, R]] |
| - | [[Category: Bycroft, M | + | [[Category: Bycroft, M]] |
| - | [[Category: Debekker, C | + | [[Category: Debekker, C]] |
| - | [[Category: Freund, S M | + | [[Category: Freund, S M]] |
| - | [[Category: Lowe, J | + | [[Category: Lowe, J]] |
| - | [[Category: Sherratt, D J | + | [[Category: Sherratt, D J]] |
| - | [[Category: Sivanathan, V | + | [[Category: Sivanathan, V]] |
[[Category: Bacterial cell division]] | [[Category: Bacterial cell division]] | ||
[[Category: Dna segregation]] | [[Category: Dna segregation]] | ||
Revision as of 20:22, 25 December 2014
PSEUDOMONAS AERUGINOSA FTSK GAMMA DOMAIN
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