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1xgw

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1xgw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XGW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XGW FirstGlance]. <br>
<table><tr><td colspan='2'>[[1xgw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XGW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XGW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EPN4, EPNR, ENTH, KIAA0171 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EPN4, EPNR, ENTH, KIAA0171 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xgw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xgw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xgw RCSB], [http://www.ebi.ac.uk/pdbsum/1xgw PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xgw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xgw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xgw RCSB], [http://www.ebi.ac.uk/pdbsum/1xgw PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/EPN4_HUMAN EPN4_HUMAN]] Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.<ref>PMID:12429846</ref> <ref>PMID:12538641</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Cygler, M.]]
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[[Category: Cygler, M]]
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[[Category: Lunin, V V.]]
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[[Category: Lunin, V V]]
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[[Category: Mazzoni, I.]]
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[[Category: Mazzoni, I]]
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[[Category: Munger, C.]]
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[[Category: Munger, C]]
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[[Category: Wagner, J.]]
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[[Category: Wagner, J]]
[[Category: Clathrin-associated]]
[[Category: Clathrin-associated]]
[[Category: Endocytosis]]
[[Category: Endocytosis]]

Revision as of 20:24, 25 December 2014

The crystal structure of human enthoprotin N-terminal domain

1xgw, resolution 1.90Å

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