1l3w

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1l3w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. The March 2008 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Cadherin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2008_3 10.2210/rcsb_pdb/mom_2008_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L3W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L3W FirstGlance]. <br>
<table><tr><td colspan='2'>[[1l3w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. The March 2008 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Cadherin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2008_3 10.2210/rcsb_pdb/mom_2008_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L3W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L3W FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ncg|1ncg]], [[1nch|1nch]], [[1nci|1nci]], [[1edh|1edh]], [[1ff5|1ff5]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ncg|1ncg]], [[1nch|1nch]], [[1nci|1nci]], [[1edh|1edh]], [[1ff5|1ff5]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l3w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l3w RCSB], [http://www.ebi.ac.uk/pdbsum/1l3w PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l3w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l3w RCSB], [http://www.ebi.ac.uk/pdbsum/1l3w PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CADHF_XENLA CADHF_XENLA]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Xenopus laevis]]
[[Category: Xenopus laevis]]
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[[Category: Boggon, T J.]]
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[[Category: Boggon, T J]]
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[[Category: Chappuis-Flament, S.]]
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[[Category: Chappuis-Flament, S]]
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[[Category: Gumbiner, B M.]]
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[[Category: Gumbiner, B M]]
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[[Category: Murray, J.]]
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[[Category: Murray, J]]
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[[Category: Shapiro, L.]]
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[[Category: Shapiro, L]]
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[[Category: Wong, E.]]
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[[Category: Wong, E]]
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[[Category: Cadherin]]
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[[Category: Calcium binding]]
[[Category: Calcium binding]]
[[Category: Cell adhesion]]
[[Category: Cell adhesion]]

Revision as of 20:26, 25 December 2014

C-cadherin Ectodomain

1l3w, resolution 3.08Å

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