2xz0

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<StructureSection load='2xz0' size='340' side='right' caption='[[2xz0]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='2xz0' size='340' side='right' caption='[[2xz0]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xz0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis] and [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZ0 OCA]. <br>
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<table><tr><td colspan='2'>[[2xz0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis] and [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XZ0 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1oq9|1oq9]], [[1oqb|1oqb]], [[1oq4|1oq4]], [[1oq7|1oq7]], [[2j2f|2j2f]], [[1afr|1afr]], [[2xz1|2xz1]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1oq9|1oq9]], [[1oqb|1oqb]], [[1oq4|1oq4]], [[1oq7|1oq7]], [[2j2f|2j2f]], [[1afr|1afr]], [[2xz1|2xz1]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acyl-[acyl-carrier-protein]_desaturase Acyl-[acyl-carrier-protein] desaturase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.19.2 1.14.19.2] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xz0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xz0 RCSB], [http://www.ebi.ac.uk/pdbsum/2xz0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xz0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xz0 RCSB], [http://www.ebi.ac.uk/pdbsum/2xz0 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/STAD_RICCO STAD_RICCO]] Converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons Delta(9) and Delta(10) of the acyl chain. [[http://www.uniprot.org/uniprot/ACP1_SPIOL ACP1_SPIOL]] Carrier of the growing fatty acid chain in fatty acid biosynthesis.[HAMAP-Rule:MF_01217]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Remote control of regioselectivity in acyl-acyl carrier protein-desaturases.,Guy JE, Whittle E, Moche M, Lengqvist J, Lindqvist Y, Shanklin J Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16594-9. Epub 2011 Sep 19. PMID:21930947<ref>PMID:21930947</ref>
Remote control of regioselectivity in acyl-acyl carrier protein-desaturases.,Guy JE, Whittle E, Moche M, Lengqvist J, Lindqvist Y, Shanklin J Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16594-9. Epub 2011 Sep 19. PMID:21930947<ref>PMID:21930947</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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[[Category: Ricinus communis]]
[[Category: Ricinus communis]]
[[Category: Spinacia oleracea]]
[[Category: Spinacia oleracea]]
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[[Category: Guy, J E.]]
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[[Category: Guy, J E]]
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[[Category: Lengqvist, J.]]
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[[Category: Lengqvist, J]]
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[[Category: Lindqvist, Y.]]
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[[Category: Lindqvist, Y]]
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[[Category: Moche, M.]]
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[[Category: Moche, M]]
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[[Category: Shanklin, J.]]
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[[Category: Shanklin, J]]
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[[Category: Whittle, E.]]
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[[Category: Whittle, E]]
[[Category: Oxidoreductase-lipid binding protein complex]]
[[Category: Oxidoreductase-lipid binding protein complex]]

Revision as of 20:28, 25 December 2014

THE STRUCTURE OF THE 2:1 (PARTIALLY OCCUPIED) COMPLEX BETWEEN STEAROYL ACYL CARRIER PROTEIN DESATURASE FROM RICINUS COMMUNIS (CASTOR BEAN) AND ACYL CARRIER PROTEIN.

2xz0, resolution 3.00Å

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