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3wan

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wan OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wan RCSB], [http://www.ebi.ac.uk/pdbsum/3wan PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wan OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wan RCSB], [http://www.ebi.ac.uk/pdbsum/3wan PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ATG13_HUMAN ATG13_HUMAN]] Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.<ref>PMID:19287211</ref> <ref>PMID:19211835</ref> <ref>PMID:19225151</ref> <ref>PMID:21855797</ref> <ref>PMID:18936157</ref> <ref>PMID:21795849</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 20:29, 25 December 2014

Crystal structure of Atg13 LIR-fused human LC3A_2-121

3wan, resolution 1.77Å

Drag the structure with the mouse to rotate

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