3g9h

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g9h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g9h RCSB], [http://www.ebi.ac.uk/pdbsum/3g9h PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g9h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g9h RCSB], [http://www.ebi.ac.uk/pdbsum/3g9h PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SYP1_YEAST SYP1_YEAST]] Multi-functional protein that contributes to the endocytic process, but also to events that occur at the neck during budding and/or cytokinesis. Plays a role as an endocytic adapters with membrane-tubulation activity that associates with transmembrane cargo proteins and initiates the formation of endocytic sites. Contributes to the stabilization of the nascent clathrin-coated pit. Plays also a role in late endocytosis by mediating vesiculation. Involved in the regulation of cell cycle-dependent dynamics of the septin cytoskeleton by promoting septin turnover in different cell cycle stages. May act through the RHO2 signaling pathway to repolarize cortical actin patches in profilin-deficient cells.<ref>PMID:11014808</ref> <ref>PMID:18791237</ref> <ref>PMID:19713939</ref> <ref>PMID:19776351</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 20:30, 25 December 2014

Crystal structure of the C-terminal mu homology domain of Syp1

3g9h, resolution 2.80Å

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