3g9h
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g9h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g9h RCSB], [http://www.ebi.ac.uk/pdbsum/3g9h PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g9h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g9h RCSB], [http://www.ebi.ac.uk/pdbsum/3g9h PDBsum]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/SYP1_YEAST SYP1_YEAST]] Multi-functional protein that contributes to the endocytic process, but also to events that occur at the neck during budding and/or cytokinesis. Plays a role as an endocytic adapters with membrane-tubulation activity that associates with transmembrane cargo proteins and initiates the formation of endocytic sites. Contributes to the stabilization of the nascent clathrin-coated pit. Plays also a role in late endocytosis by mediating vesiculation. Involved in the regulation of cell cycle-dependent dynamics of the septin cytoskeleton by promoting septin turnover in different cell cycle stages. May act through the RHO2 signaling pathway to repolarize cortical actin patches in profilin-deficient cells.<ref>PMID:11014808</ref> <ref>PMID:18791237</ref> <ref>PMID:19713939</ref> <ref>PMID:19776351</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] |
Revision as of 20:30, 25 December 2014
Crystal structure of the C-terminal mu homology domain of Syp1
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Categories: Saccharomyces cerevisiae | Barker, S | Hurley, J | Im, Y J | Maldonado-Baez, L | Mishra, S | Reider, A | Traub, L | Wendland, B | Adaptor | Endocytosis | Mu | Phosphoprotein | Syp1