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4utn

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4utn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4utn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4utn RCSB], [http://www.ebi.ac.uk/pdbsum/4utn PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4utn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4utn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4utn RCSB], [http://www.ebi.ac.uk/pdbsum/4utn PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SIR5_DANRE SIR5_DANRE]] NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Gertz, M.]]
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[[Category: Gertz, M]]
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[[Category: Pannek, M.]]
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[[Category: Pannek, M]]
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[[Category: Steegborn, C.]]
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[[Category: Steegborn, C]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Regulatory enzyme]]
[[Category: Regulatory enzyme]]
[[Category: Rossmann-fold]]
[[Category: Rossmann-fold]]
[[Category: Zinc-binding]]
[[Category: Zinc-binding]]

Revision as of 20:33, 25 December 2014

Crystal structure of zebrafish Sirtuin 5 in complex with succinylated CPS1-peptide

4utn, resolution 3.00Å

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