2f87

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[[Image:2f87.gif|left|200px]]<br /><applet load="2f87" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2f87.gif|left|200px]]
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caption="2f87" />
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'''Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus'''<br />
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{{Structure
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|PDB= 2f87 |SIZE=350|CAPTION= <scene name='initialview01'>2f87</scene>
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2F87 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F87 OCA].
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2F87 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F87 OCA].
==Reference==
==Reference==
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Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus., Okada K, Takahashi M, Sakamoto T, Kawai G, Nakamura K, Kanai A, Nucleosides Nucleotides Nucleic Acids. 2006;25(4-6):383-95. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16838833 16838833]
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Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus., Okada K, Takahashi M, Sakamoto T, Kawai G, Nakamura K, Kanai A, Nucleosides Nucleotides Nucleic Acids. 2006;25(4-6):383-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16838833 16838833]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Kanai, A.]]
[[Category: Kanai, A.]]
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[[Category: srp]]
[[Category: srp]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:18:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:49:16 2008''

Revision as of 14:49, 20 March 2008

Image:2f87.gif


PDB ID 2f87

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Coordinates: save as pdb, mmCIF, xml



Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus


Overview

The NMR structure of a 12-mer RNA derived from the helix 6 of SRP RNA from Pyrococcus furiosus, whose loop-closing base pair is U.G, was determined, and the structural and thermodynamic properties of the RNA were compared with those of a mutant RNA with the C:G closing base pair. Although the structures of the two RNAs are similar to each other and adopt the GNRR motif the conformational stabilities are significantly different to each other It was suggested that weaker stacking interaction of the GAAG loop with the U:G closing base pair in 12-mer RNA causes the lower conformational stability.

About this Structure

2F87 is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus., Okada K, Takahashi M, Sakamoto T, Kawai G, Nakamura K, Kanai A, Nucleosides Nucleotides Nucleic Acids. 2006;25(4-6):383-95. PMID:16838833

Page seeded by OCA on Thu Mar 20 16:49:16 2008

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