2f8m

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[[Image:2f8m.gif|left|200px]]<br /><applet load="2f8m" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2f8m.gif|left|200px]]
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caption="2f8m, resolution 2.087&Aring;" />
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'''Ribose 5-phosphate isomerase from Plasmodium falciparum'''<br />
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{{Structure
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|PDB= 2f8m |SIZE=350|CAPTION= <scene name='initialview01'>2f8m</scene>, resolution 2.087&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE ION'>PO4</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Ribose-5-phosphate_isomerase Ribose-5-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.6 5.3.1.6]
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|GENE= PFE0730c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 Plasmodium falciparum 3D7])
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}}
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'''Ribose 5-phosphate isomerase from Plasmodium falciparum'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2F8M is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7] with <scene name='pdbligand=PO4:'>PO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Ribose-5-phosphate_isomerase Ribose-5-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.6 5.3.1.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8M OCA].
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2F8M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8M OCA].
==Reference==
==Reference==
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Structure of ribose 5-phosphate isomerase from Plasmodium falciparum., Holmes MA, Buckner FS, Van Voorhis WC, Verlinde CL, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Earnest TN, Hol WG, Merritt EA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):427-31. Epub 2006 Apr 12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16682767 16682767]
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Structure of ribose 5-phosphate isomerase from Plasmodium falciparum., Holmes MA, Buckner FS, Van Voorhis WC, Verlinde CL, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Earnest TN, Hol WG, Merritt EA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):427-31. Epub 2006 Apr 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16682767 16682767]
[[Category: Plasmodium falciparum 3d7]]
[[Category: Plasmodium falciparum 3d7]]
[[Category: Ribose-5-phosphate isomerase]]
[[Category: Ribose-5-phosphate isomerase]]
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[[Category: psi]]
[[Category: psi]]
[[Category: sgpp]]
[[Category: sgpp]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: structural genomics of pathogenic protozoa consortium]]
[[Category: structural genomics of pathogenic protozoa consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:18:51 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:49:24 2008''

Revision as of 14:49, 20 March 2008


PDB ID 2f8m

Drag the structure with the mouse to rotate
, resolution 2.087Å
Ligands:
Gene: PFE0730c (Plasmodium falciparum 3D7)
Activity: Ribose-5-phosphate isomerase, with EC number 5.3.1.6
Coordinates: save as pdb, mmCIF, xml



Ribose 5-phosphate isomerase from Plasmodium falciparum


Overview

The structure of ribose 5-phosphate isomerase from Plasmodium falciparum, PFE0730c, has been determined by molecular replacement at 2.09 angstroms resolution. The enzyme, which catalyzes the isomerization reaction that interconverts ribose 5-phosphate and ribulose 5-phosphate, is a member of the pentose phosphate pathway. The P. falciparum enzyme belongs to the ribose 5-phosphate isomerase A family, Pfam family PF06562 (DUF1124), and is structurally similar to other members of the family.

About this Structure

2F8M is a Single protein structure of sequence from Plasmodium falciparum 3d7. Full crystallographic information is available from OCA.

Reference

Structure of ribose 5-phosphate isomerase from Plasmodium falciparum., Holmes MA, Buckner FS, Van Voorhis WC, Verlinde CL, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Earnest TN, Hol WG, Merritt EA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):427-31. Epub 2006 Apr 12. PMID:16682767

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