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2yt7
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2yt7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YT7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YT7 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2yt7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YT7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YT7 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APBA3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APBA3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yt7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yt7 RCSB], [http://www.ebi.ac.uk/pdbsum/2yt7 PDBsum], [http://www.topsan.org/Proteins/RSGI/2yt7 TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yt7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yt7 RCSB], [http://www.ebi.ac.uk/pdbsum/2yt7 PDBsum], [http://www.topsan.org/Proteins/RSGI/2yt7 TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/APBA3_HUMAN APBA3_HUMAN]] May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.<ref>PMID:19726677</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Dang, W | + | [[Category: Dang, W]] |
| - | [[Category: Inoue, M | + | [[Category: Inoue, M]] |
| - | [[Category: Kigawa, T | + | [[Category: Kigawa, T]] |
| - | [[Category: Muto, Y | + | [[Category: Muto, Y]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Seiki, M | + | [[Category: Seiki, M]] |
| - | [[Category: Shirouzu, M | + | [[Category: Shirouzu, M]] |
| - | [[Category: Tarada, T | + | [[Category: Tarada, T]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Adapter protein x11gamma]] | [[Category: Adapter protein x11gamma]] | ||
[[Category: Amyloid beta a4 precursor protein-binding family a member 3]] | [[Category: Amyloid beta a4 precursor protein-binding family a member 3]] | ||
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[[Category: Pdz domain]] | [[Category: Pdz domain]] | ||
[[Category: Protein transport]] | [[Category: Protein transport]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
Revision as of 20:40, 25 December 2014
Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3
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Categories: Homo sapiens | Dang, W | Inoue, M | Kigawa, T | Muto, Y | Structural genomic | Seiki, M | Shirouzu, M | Tarada, T | Yokoyama, S | Adapter protein x11gamma | Amyloid beta a4 precursor protein-binding family a member 3 | Mint-3 | National project on protein structural and functional analyse | Neuron-specific x11l2 protein | Neuronal munc18-1-interacting protein 3 | Nppsfa | Pdz domain | Protein transport | Rsgi
