1xbw
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1xbw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mw2 Staphylococcus aureus subsp. aureus mw2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XBW FirstGlance]. <br> | <table><tr><td colspan='2'>[[1xbw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mw2 Staphylococcus aureus subsp. aureus mw2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XBW FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sue|1sue]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sue|1sue]]</td></tr> |
- | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GI:1003130 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196620 Staphylococcus aureus subsp. aureus MW2])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GI:1003130 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196620 Staphylococcus aureus subsp. aureus MW2])</td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xbw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xbw RCSB], [http://www.ebi.ac.uk/pdbsum/1xbw PDBsum], [http://www.topsan.org/Proteins/MCSG/1xbw TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xbw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xbw RCSB], [http://www.ebi.ac.uk/pdbsum/1xbw PDBsum], [http://www.topsan.org/Proteins/MCSG/1xbw TOPSAN]</span></td></tr> |
- | <table> | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/ISDG_STAAW ISDG_STAAW]] Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity).<ref>PMID:15520015</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Staphylococcus aureus subsp. aureus mw2]] | [[Category: Staphylococcus aureus subsp. aureus mw2]] | ||
- | [[Category: Joachimiak, A | + | [[Category: Joachimiak, A]] |
- | [[Category: Joachimiak, G | + | [[Category: Joachimiak, G]] |
- | [[Category: | + | [[Category: Structural genomic]] |
- | [[Category: Schneewind, O | + | [[Category: Schneewind, O]] |
- | [[Category: Wu, R | + | [[Category: Wu, R]] |
- | [[Category: Zhang, R | + | [[Category: Zhang, R]] |
[[Category: Mcsg]] | [[Category: Mcsg]] | ||
- | [[Category: Midwest center for structural genomic]] | ||
[[Category: Protein isdg]] | [[Category: Protein isdg]] | ||
- | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
- | + | ||
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
- | [[Category: Structural genomic]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] |
Revision as of 20:40, 25 December 2014
1.9A Crystal Structure of the protein isdG from Staphylococcus aureus aureus, Structural genomics, MCSG
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