1xbw

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1xbw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mw2 Staphylococcus aureus subsp. aureus mw2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XBW FirstGlance]. <br>
<table><tr><td colspan='2'>[[1xbw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mw2 Staphylococcus aureus subsp. aureus mw2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XBW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sue|1sue]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sue|1sue]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GI:1003130 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196620 Staphylococcus aureus subsp. aureus MW2])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GI:1003130 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196620 Staphylococcus aureus subsp. aureus MW2])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xbw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xbw RCSB], [http://www.ebi.ac.uk/pdbsum/1xbw PDBsum], [http://www.topsan.org/Proteins/MCSG/1xbw TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xbw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xbw RCSB], [http://www.ebi.ac.uk/pdbsum/1xbw PDBsum], [http://www.topsan.org/Proteins/MCSG/1xbw TOPSAN]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ISDG_STAAW ISDG_STAAW]] Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity).<ref>PMID:15520015</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Staphylococcus aureus subsp. aureus mw2]]
[[Category: Staphylococcus aureus subsp. aureus mw2]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak, A]]
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[[Category: Joachimiak, G.]]
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[[Category: Joachimiak, G]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Structural genomic]]
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[[Category: Schneewind, O.]]
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[[Category: Schneewind, O]]
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[[Category: Wu, R.]]
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[[Category: Wu, R]]
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[[Category: Zhang, R.]]
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[[Category: Zhang, R]]
[[Category: Mcsg]]
[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
 
[[Category: Protein isdg]]
[[Category: Protein isdg]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Structural genomic]]
 
[[Category: Unknown function]]
[[Category: Unknown function]]

Revision as of 20:40, 25 December 2014

1.9A Crystal Structure of the protein isdG from Staphylococcus aureus aureus, Structural genomics, MCSG

1xbw, resolution 1.90Å

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