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2w73
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2w73]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W73 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W73 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2w73]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W73 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W73 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j7p|1j7p]], [[2f3z|2f3z]], [[1mf8|1mf8]], [[1nkf|1nkf]], [[2jl2|2jl2]], [[1xfv|1xfv]], [[1k93|1k93]], [[1sk6|1sk6]], [[1y6w|1y6w]], [[1iwq|1iwq]], [[1k90|1k90]], [[1yrt|1yrt]], [[1lvc|1lvc]], [[1cll|1cll]], [[1cdl|1cdl]], [[1xfu|1xfu]], [[1xfy|1xfy]], [[2f3y|2f3y]], [[1xfx|1xfx]], [[1s26|1s26]], [[1j7o|1j7o]], [[1aui|1aui]], [[1yru|1yru]], [[1wrz|1wrz]], [[2v02|2v02]], [[1xfz|1xfz]], [[1xfw|1xfw]], [[2v01|2v01]], [[1pk0|1pk0]], [[1m63|1m63]], [[2be6|2be6]], [[1zot|1zot]], [[1sw8|1sw8]], [[2vay|2vay]], [[1aji|1aji]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j7p|1j7p]], [[2f3z|2f3z]], [[1mf8|1mf8]], [[1nkf|1nkf]], [[2jl2|2jl2]], [[1xfv|1xfv]], [[1k93|1k93]], [[1sk6|1sk6]], [[1y6w|1y6w]], [[1iwq|1iwq]], [[1k90|1k90]], [[1yrt|1yrt]], [[1lvc|1lvc]], [[1cll|1cll]], [[1cdl|1cdl]], [[1xfu|1xfu]], [[1xfy|1xfy]], [[2f3y|2f3y]], [[1xfx|1xfx]], [[1s26|1s26]], [[1j7o|1j7o]], [[1aui|1aui]], [[1yru|1yru]], [[1wrz|1wrz]], [[2v02|2v02]], [[1xfz|1xfz]], [[1xfw|1xfw]], [[2v01|2v01]], [[1pk0|1pk0]], [[1m63|1m63]], [[2be6|2be6]], [[1zot|1zot]], [[1sw8|1sw8]], [[2vay|2vay]], [[1aji|1aji]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w73 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w73 RCSB], [http://www.ebi.ac.uk/pdbsum/2w73 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w73 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w73 RCSB], [http://www.ebi.ac.uk/pdbsum/2w73 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PP2BA_HUMAN PP2BA_HUMAN]] Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.<ref>PMID:15671020</ref> <ref>PMID:18838687</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phosphoprotein phosphatase]] | [[Category: Phosphoprotein phosphatase]] | ||
| - | [[Category: Kursula, P | + | [[Category: Kursula, P]] |
| - | [[Category: Majava, V | + | [[Category: Majava, V]] |
[[Category: Calmodulin]] | [[Category: Calmodulin]] | ||
[[Category: Calmodulin-binding]] | [[Category: Calmodulin-binding]] | ||
Revision as of 20:56, 25 December 2014
HIGH-RESOLUTION STRUCTURE OF THE COMPLEX BETWEEN CALMODULIN AND A PEPTIDE FROM CALCINEURIN A
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