4eq6
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4eq6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EQ6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4eq6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EQ6 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSM2, YIL132C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae]), PSY3, YLR376C, L8039.17 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSM2, YIL132C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae]), PSY3, YLR376C, L8039.17 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/4eq6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eq6 RCSB], [http://www.ebi.ac.uk/pdbsum/4eq6 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CSM2_YEAST CSM2_YEAST]] Involved in chromosome segregation during meiosis. Promotes efficient recombinational repair and functions in the protection of the genome from spontaneous and induced DNA damage like mutations and gross chromosomal rearrangements (GCRs).<ref>PMID:11470404</ref> <ref>PMID:12972632</ref> <ref>PMID:15184655</ref> <ref>PMID:15654096</ref> <ref>PMID:19496932</ref> [[http://www.uniprot.org/uniprot/PSY3_YEAST PSY3_YEAST]] Required for resistance to the DNA-damaging agents methyl methanesulfonate (MMS), cisplatin and oxaliplatin, but not to mitomycin C. Plays a role in protection against mutation accumulation. May be a component of the recombination-repair pathway.<ref>PMID:12149442</ref> <ref>PMID:12482937</ref> <ref>PMID:12972632</ref> <ref>PMID:15173006</ref> <ref>PMID:15654096</ref> <ref>PMID:19496932</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Dong, Y H | + | [[Category: Dong, Y H]] |
| - | [[Category: Gao, Z Q | + | [[Category: Gao, Z Q]] |
| - | [[Category: She, Z | + | [[Category: She, Z]] |
[[Category: Dna binding protein]] | [[Category: Dna binding protein]] | ||
Revision as of 20:59, 25 December 2014
The crystal structure of Psy3-Csm2 complex from budding yeast
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