1r8g

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1r8g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1R8G FirstGlance]. <br>
<table><tr><td colspan='2'>[[1r8g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1R8G FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YBDK, B0581 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YBDK, B0581 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r8g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1r8g RCSB], [http://www.ebi.ac.uk/pdbsum/1r8g PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r8g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1r8g RCSB], [http://www.ebi.ac.uk/pdbsum/1r8g PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CAAL_ECOLI CAAL_ECOLI]] ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity. However, because of the low catalytic rate, the question remains whether L-cysteine is the actual biological substrate.<ref>PMID:15211520</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Doseeva, V.]]
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[[Category: Doseeva, V]]
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[[Category: Herzberg, O.]]
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[[Category: Herzberg, O]]
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[[Category: Howard, A.]]
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[[Category: Howard, A]]
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[[Category: Krajewski, W.]]
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[[Category: Krajewski, W]]
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[[Category: Lehmann, C.]]
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[[Category: Lehmann, C]]
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[[Category: Pullalarevu, S.]]
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[[Category: Pullalarevu, S]]
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[[Category: S2F, Structure 2.Function Project.]]
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[[Category: S2F, Structure 2.Function Project]]
[[Category: Carboxylate-amine ligase]]
[[Category: Carboxylate-amine ligase]]
[[Category: Hypothetical protein]]
[[Category: Hypothetical protein]]

Revision as of 21:01, 25 December 2014

Structure and function of YbdK

1r8g, resolution 2.15Å

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