2lui

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{{STRUCTURE_2lui| PDB=2lui | SCENE= }}
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==Structure of the PICK PDZ domain in complex with the DAT C-terminal==
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===Structure of the PICK PDZ domain in complex with the DAT C-terminal===
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<StructureSection load='2lui' size='340' side='right' caption='[[2lui]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[2lui]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LUI FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Pick1, Prkcabp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lui OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lui RCSB], [http://www.ebi.ac.uk/pdbsum/2lui PDBsum]</span></td></tr>
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</table>
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== Function ==
[[http://www.uniprot.org/uniprot/PICK1_RAT PICK1_RAT]] Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel.<ref>PMID:16138078</ref>
[[http://www.uniprot.org/uniprot/PICK1_RAT PICK1_RAT]] Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel.<ref>PMID:16138078</ref>
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== References ==
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==About this Structure==
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<references/>
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[[2lui]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUI OCA].
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__TOC__
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</StructureSection>
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Erlendsson, S.]]
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[[Category: Erlendsson, S]]
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[[Category: Gether, U.]]
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[[Category: Gether, U]]
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[[Category: Heidarsson, P O.]]
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[[Category: Heidarsson, P O]]
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[[Category: Madsen, K L.]]
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[[Category: Madsen, K L]]
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[[Category: Poulsen, F M.]]
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[[Category: Poulsen, F M]]
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[[Category: Rathje, M.]]
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[[Category: Rathje, M]]
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[[Category: Teilum, K.]]
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[[Category: Teilum, K]]
[[Category: Dat c-terminal]]
[[Category: Dat c-terminal]]
[[Category: Pdz]]
[[Category: Pdz]]
[[Category: Pick1]]
[[Category: Pick1]]
[[Category: Protein binding]]
[[Category: Protein binding]]

Revision as of 21:15, 25 December 2014

Structure of the PICK PDZ domain in complex with the DAT C-terminal

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