2zlf

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zlf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZLF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zlf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZLF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zlg|2zlg]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zlg|2zlg]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zlf RCSB], [http://www.ebi.ac.uk/pdbsum/2zlf PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zlf RCSB], [http://www.ebi.ac.uk/pdbsum/2zlf PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RIR1_YEAST RIR1_YEAST]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.<ref>PMID:11893751</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Ribonucleoside-diphosphate reductase]]
[[Category: Ribonucleoside-diphosphate reductase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Cooperman, B S.]]
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[[Category: Cooperman, B S]]
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[[Category: Dealwis, C.]]
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[[Category: Dealwis, C]]
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[[Category: Fairman, J W.]]
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[[Category: Fairman, J W]]
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[[Category: Helmbrecht, E.]]
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[[Category: Helmbrecht, E]]
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[[Category: Kreischer, N R.]]
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[[Category: Kreischer, N R]]
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[[Category: LaMacchia, J.]]
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[[Category: LaMacchia, J]]
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[[Category: Wijerathna, S R.]]
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[[Category: Wijerathna, S R]]
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[[Category: Xu, H.]]
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[[Category: Xu, H]]
[[Category: Allosteric enzyme]]
[[Category: Allosteric enzyme]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]

Revision as of 21:16, 25 December 2014

The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase

2zlf, resolution 2.59Å

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