4gum
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gum OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gum RCSB], [http://www.ebi.ac.uk/pdbsum/4gum PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gum OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gum RCSB], [http://www.ebi.ac.uk/pdbsum/4gum PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MIF_MACMU MIF_MACMU]] Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 21:23, 25 December 2014
Cystal structure of locked-trimer of human MIF
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