2ffh

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[[Image:2ffh.gif|left|200px]]<br /><applet load="2ffh" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2ffh.gif|left|200px]]
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caption="2ffh, resolution 3.2&Aring;" />
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'''THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS'''<br />
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{{Structure
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|PDB= 2ffh |SIZE=350|CAPTION= <scene name='initialview01'>2ffh</scene>, resolution 3.2&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene> and <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2FFH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus] with <scene name='pdbligand=CD:'>CD</scene> and <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FFH OCA].
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2FFH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FFH OCA].
==Reference==
==Reference==
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Crystal structure of the signal sequence binding subunit of the signal recognition particle., Keenan RJ, Freymann DM, Walter P, Stroud RM, Cell. 1998 Jul 24;94(2):181-91. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9695947 9695947]
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Crystal structure of the signal sequence binding subunit of the signal recognition particle., Keenan RJ, Freymann DM, Walter P, Stroud RM, Cell. 1998 Jul 24;94(2):181-91. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9695947 9695947]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
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[[Category: srp54]]
[[Category: srp54]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:20:53 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:51:46 2008''

Revision as of 14:51, 20 March 2008

Image:2ffh.gif


PDB ID 2ffh

Drag the structure with the mouse to rotate
, resolution 3.2Å
Ligands: and
Coordinates: save as pdb, mmCIF, xml



THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS


Overview

The crystal structure of the signal sequence binding subunit of the signal recognition particle (SRP) from Thermus aquaticus reveals a deep groove bounded by a flexible loop and lined with side chains of conserved hydrophobic residues. The groove defines a flexible, hydrophobic environment that is likely to contribute to the structural plasticity necessary for SRP to bind signal sequences of different lengths and amino acid sequence. The structure also reveals a helix-turn-helix motif containing an arginine-rich alpha helix that is required for binding to SRP RNA and is implicated in forming the core of an extended RNA binding surface.

About this Structure

2FFH is a Single protein structure of sequence from Thermus aquaticus. Full crystallographic information is available from OCA.

Reference

Crystal structure of the signal sequence binding subunit of the signal recognition particle., Keenan RJ, Freymann DM, Walter P, Stroud RM, Cell. 1998 Jul 24;94(2):181-91. PMID:9695947

Page seeded by OCA on Thu Mar 20 16:51:46 2008

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