4f1p

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f1p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4f1p RCSB], [http://www.ebi.ac.uk/pdbsum/4f1p PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f1p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4f1p RCSB], [http://www.ebi.ac.uk/pdbsum/4f1p PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ACAP1_HUMAN ACAP1_HUMAN]] GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.<ref>PMID:11062263</ref> <ref>PMID:16256741</ref> <ref>PMID:17398097</ref> <ref>PMID:17664335</ref> <ref>PMID:22645133</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 21:31, 25 December 2014

Crystal Structure of mutant S554D for ArfGAP and ANK repeat domain of ACAP1

4f1p, resolution 2.30Å

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