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3e0j

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3e0j]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E0J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3E0J FirstGlance]. <br>
<table><tr><td colspan='2'>[[3e0j]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E0J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3E0J FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e0j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3e0j RCSB], [http://www.ebi.ac.uk/pdbsum/3e0j PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e0j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3e0j RCSB], [http://www.ebi.ac.uk/pdbsum/3e0j PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DPOD2_HUMAN DPOD2_HUMAN]] The function of the small subunit is not yet clear. [[http://www.uniprot.org/uniprot/DPOD3_HUMAN DPOD3_HUMAN]] Required for optimal DNA polymerase delta activity.<ref>PMID:10219083</ref> <ref>PMID:10852724</ref> <ref>PMID:16510448</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Babayeva, N D.]]
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[[Category: Babayeva, N D]]
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[[Category: Baranovskiy, A G.]]
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[[Category: Baranovskiy, A G]]
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[[Category: Pavlov, Y I.]]
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[[Category: Pavlov, Y I]]
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[[Category: Tahirov, T H.]]
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[[Category: Tahirov, T H]]
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[[Category: Vassylyev, D G.]]
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[[Category: Vassylyev, D G]]
[[Category: Dna polymerase delta]]
[[Category: Dna polymerase delta]]
[[Category: Dna replication]]
[[Category: Dna replication]]

Revision as of 21:33, 25 December 2014

X-ray structure of the complex of regulatory subunits of human DNA polymerase delta

3e0j, resolution 3.00Å

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