4f6o

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[[Image:4f6o.jpg|left|200px]]
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==Crystal structure of the yeast metacaspase Yca1==
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<StructureSection load='4f6o' size='340' side='right' caption='[[4f6o]], [[Resolution|resolution]] 1.68&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4f6o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4F6O FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DFH:1,1-DIPHENYLETHANOL'>DFH</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MCA1, YCA1, YOR197W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f6o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4f6o RCSB], [http://www.ebi.ac.uk/pdbsum/4f6o PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MCA1_YEAST MCA1_YEAST]] Mediates cell death (apoptosis) triggered by oxygen stress, salt stress or chronological aging. Regulated cell death can prevent a release of toxic cellular components, thus avoiding necrotic collapse of the colony, and can also provide nutrients for healthy cells. Therefore, regulated cell death in yeast colonies can be as important for their development as are apoptosis and related processes that occur within metazoa. Promotes the removal of insoluble protein aggregates during normal growth.<ref>PMID:11983181</ref> <ref>PMID:15489197</ref> <ref>PMID:15381687</ref> <ref>PMID:14970189</ref> <ref>PMID:14718573</ref> <ref>PMID:16170310</ref> <ref>PMID:15668299</ref> <ref>PMID:15939758</ref> <ref>PMID:16079294</ref> <ref>PMID:16301538</ref> <ref>PMID:20624963</ref>
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{{STRUCTURE_4f6o| PDB=4f6o | SCENE= }}
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==See Also==
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*[[Caspase|Caspase]]
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===Crystal structure of the yeast metacaspase Yca1===
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== References ==
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<references/>
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4f6o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F6O OCA].
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Shi, Y G.]]
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[[Category: Shi, Y G]]
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[[Category: Wong, A H.]]
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[[Category: Wong, A H]]
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[[Category: Yan, C Y.]]
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[[Category: Yan, C Y]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Metacaspase]]
[[Category: Metacaspase]]
[[Category: Rossmann fold]]
[[Category: Rossmann fold]]

Revision as of 21:38, 25 December 2014

Crystal structure of the yeast metacaspase Yca1

4f6o, resolution 1.68Å

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