3peq
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3peq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3peq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3peq RCSB], [http://www.ebi.ac.uk/pdbsum/3peq PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3peq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3peq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3peq RCSB], [http://www.ebi.ac.uk/pdbsum/3peq PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PPARD_HUMAN PPARD_HUMAN]] Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.<ref>PMID:1333051</ref> <ref>PMID:15604518</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| - | [[Category: Billin, A N | + | [[Category: Billin, A N]] |
| - | [[Category: Britt, C | + | [[Category: Britt, C]] |
| - | [[Category: Evans, K A | + | [[Category: Evans, K A]] |
| - | [[Category: Jin, J | + | [[Category: Jin, J]] |
| - | [[Category: Lambert, M H | + | [[Category: Lambert, M H]] |
| - | [[Category: Leesnitzer, L M | + | [[Category: Leesnitzer, L M]] |
| - | [[Category: Merrihew, R V | + | [[Category: Merrihew, R V]] |
| - | [[Category: Rivero, R A | + | [[Category: Rivero, R A]] |
| - | [[Category: Shearer, B G | + | [[Category: Shearer, B G]] |
| - | [[Category: Shi, D | + | [[Category: Shi, D]] |
| - | [[Category: Sparks, S M | + | [[Category: Sparks, S M]] |
| - | [[Category: Way, J M | + | [[Category: Way, J M]] |
| - | [[Category: Winegar, D A | + | [[Category: Winegar, D A]] |
| - | [[Category: Wisnoski, D D | + | [[Category: Wisnoski, D D]] |
[[Category: Ppar nuclear receptor]] | [[Category: Ppar nuclear receptor]] | ||
[[Category: Transcription-transcription agonist complex]] | [[Category: Transcription-transcription agonist complex]] | ||
Revision as of 21:39, 25 December 2014
PPARd complexed with a phenoxyacetic acid partial agonist
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