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2cbf

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cbf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CBF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CBF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cbf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CBF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CBF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CBIF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1404 Bacillus megaterium])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CBIF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1404 Bacillus megaterium])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Precorrin-4_C(11)-methyltransferase Precorrin-4 C(11)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.133 2.1.1.133] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Precorrin-4_C(11)-methyltransferase Precorrin-4 C(11)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.133 2.1.1.133] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cbf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cbf RCSB], [http://www.ebi.ac.uk/pdbsum/2cbf PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cbf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cbf RCSB], [http://www.ebi.ac.uk/pdbsum/2cbf PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CBIF_BACME CBIF_BACME]] Catalyzes the methylation of C-11 in cobalt-precorrin-4 to form cobalt-precorrin-5A.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Bacillus megaterium]]
[[Category: Bacillus megaterium]]
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[[Category: Raux, E.]]
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[[Category: Raux, E]]
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[[Category: Schubert, H L.]]
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[[Category: Schubert, H L]]
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[[Category: Warren, M J.]]
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[[Category: Warren, M J]]
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[[Category: Wilson, K S.]]
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[[Category: Wilson, K S]]
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[[Category: Woodcock, S C.]]
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[[Category: Woodcock, S C]]
[[Category: Cobalamin biosynthesis]]
[[Category: Cobalamin biosynthesis]]
[[Category: Methylase]]
[[Category: Methylase]]
[[Category: Methyltransferase]]
[[Category: Methyltransferase]]
[[Category: Precorrin-4 methyltransferase]]
[[Category: Precorrin-4 methyltransferase]]

Revision as of 21:46, 25 December 2014

THE X-RAY STRUCTURE OF A COBALAMIN BIOSYNTHETIC ENZYME, COBALT PRECORRIN-4 METHYLTRANSFERASE, CBIF, FROM BACILLUS MEGATERIUM, WITH THE HIS-TAG CLEAVED OFF

2cbf, resolution 3.10Å

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