4cjm

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<StructureSection load='4cjm' size='340' side='right' caption='[[4cjm]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4cjm' size='340' side='right' caption='[[4cjm]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4cjm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CJM OCA]. <br>
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<table><tr><td colspan='2'>[[4cjm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CJM FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cjm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cjm RCSB], [http://www.ebi.ac.uk/pdbsum/4cjm PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cjm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cjm RCSB], [http://www.ebi.ac.uk/pdbsum/4cjm PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FGF18_HUMAN FGF18_HUMAN]] Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.<ref>PMID:16597617</ref>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Adam, L E.]]
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[[Category: Adam, L E]]
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[[Category: Blundell, T L.]]
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[[Category: Blundell, T L]]
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[[Category: Brown, A.]]
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[[Category: Brown, A]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]
[[Category: Signalling]]
[[Category: Signalling]]

Revision as of 21:52, 25 December 2014

Crystal structure of human FGF18

4cjm, resolution 2.70Å

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