1p7j
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1p7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P7J FirstGlance]. <br> | <table><tr><td colspan='2'>[[1p7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P7J FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1enh|1enh]], [[3hdd|3hdd]], [[1duo|1duo]], [[2hdd|2hdd]], [[1p7i|1p7i]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1enh|1enh]], [[3hdd|3hdd]], [[1duo|1duo]], [[2hdd|2hdd]], [[1p7i|1p7i]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p7j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p7j RCSB], [http://www.ebi.ac.uk/pdbsum/1p7j PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p7j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p7j RCSB], [http://www.ebi.ac.uk/pdbsum/1p7j PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME]] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
| - | [[Category: Federici, L | + | [[Category: Federici, L]] |
| - | [[Category: Fersht, A R | + | [[Category: Fersht, A R]] |
| - | [[Category: Freund, S M | + | [[Category: Freund, S M]] |
| - | [[Category: Lovell, S C | + | [[Category: Lovell, S C]] |
| - | [[Category: Luisi, B F | + | [[Category: Luisi, B F]] |
| - | [[Category: Mayor, U | + | [[Category: Mayor, U]] |
| - | [[Category: Stollar, E J | + | [[Category: Stollar, E J]] |
[[Category: Dna binding protein]] | [[Category: Dna binding protein]] | ||
Revision as of 21:56, 25 December 2014
Crystal structure of engrailed homeodomain mutant K52E
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