1tzf

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1tzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhi Salmonella enterica subsp. enterica serovar typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TZF FirstGlance]. <br>
<table><tr><td colspan='2'>[[1tzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhi Salmonella enterica subsp. enterica serovar typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TZF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C5G:[CYTIDINE-5-PHOSPHATE]-BETA-GLUCOSYL-PHOSPHORIC+ACID+ESTER'>C5G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C5G:[CYTIDINE-5-PHOSPHATE]-BETA-GLUCOSYL-PHOSPHORIC+ACID+ESTER'>C5G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rfbF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90370 Salmonella enterica subsp. enterica serovar Typhi])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rfbF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90370 Salmonella enterica subsp. enterica serovar Typhi])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_cytidylyltransferase Glucose-1-phosphate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.33 2.7.7.33] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_cytidylyltransferase Glucose-1-phosphate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.33 2.7.7.33] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tzf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tzf RCSB], [http://www.ebi.ac.uk/pdbsum/1tzf PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tzf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tzf RCSB], [http://www.ebi.ac.uk/pdbsum/1tzf PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RFBF_SALTY RFBF_SALTY]] Involved in the biosynthesis of the tyvelose, a 3,6-dideoxyhexose found in the O-antigen of the surface lipopolysaccharides. It catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Glucose-1-phosphate cytidylyltransferase]]
[[Category: Glucose-1-phosphate cytidylyltransferase]]
[[Category: Salmonella enterica subsp. enterica serovar typhi]]
[[Category: Salmonella enterica subsp. enterica serovar typhi]]
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[[Category: Holden, H M.]]
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[[Category: Holden, H M]]
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[[Category: Koropatkin, N M.]]
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[[Category: Koropatkin, N M]]
[[Category: Mixed alpha/beta fold]]
[[Category: Mixed alpha/beta fold]]
[[Category: Nucleotidyltransferase]]
[[Category: Nucleotidyltransferase]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 22:08, 25 December 2014

X-ray Crystal Structure of alpha-D-glucose-1-phosphate cytidylyltransferase from Salmonella typhi

1tzf, resolution 2.10Å

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