2xvy
From Proteopedia
(Difference between revisions)
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<StructureSection load='2xvy' size='340' side='right' caption='[[2xvy]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='2xvy' size='340' side='right' caption='[[2xvy]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xvy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XVY OCA]. <br> | + | <table><tr><td colspan='2'>[[2xvy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XVY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XVY FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PER:PEROXIDE+ION'>PER</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PER:PEROXIDE+ION'>PER</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sirohydrochlorin_cobaltochelatase Sirohydrochlorin cobaltochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.3 4.99.1.3] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xvy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xvy RCSB], [http://www.ebi.ac.uk/pdbsum/2xvy PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xvy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xvy RCSB], [http://www.ebi.ac.uk/pdbsum/2xvy PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q72EC8_DESVH Q72EC8_DESVH]] Catalyzes the insertion of Co(2+) into sirohydrochlorin. To a lesser extent, is also able to insert Fe(2+) into sirohydrochlorin, yielding siroheme. Its periplasmic location means that it cannot participate in cobalamin biosynthesis and its genomic environment suggests it is likely to be associated with a heme or metal transport system. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Desulfovibrio vulgaris]] | [[Category: Desulfovibrio vulgaris]] | ||
[[Category: Sirohydrochlorin cobaltochelatase]] | [[Category: Sirohydrochlorin cobaltochelatase]] | ||
| - | [[Category: Carrondo, M A | + | [[Category: Carrondo, M A]] |
| - | [[Category: Lobo, S A.L | + | [[Category: Lobo, S A.L]] |
| - | [[Category: Matias, P M | + | [[Category: Matias, P M]] |
| - | [[Category: Romao, C V | + | [[Category: Romao, C V]] |
| - | [[Category: Saraiva, L M | + | [[Category: Saraiva, L M]] |
[[Category: Metal binding protein]] | [[Category: Metal binding protein]] | ||
Revision as of 22:11, 25 December 2014
COBALT CHELATASE CBIK (PERIPLASMATIC) FROM DESULVOBRIO VULGARIS HILDENBOROUGH (CO-CRYSTALLISED WITH COBALT AND SHC)
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