4oys

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oys FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oys OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oys RCSB], [http://www.ebi.ac.uk/pdbsum/4oys PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oys FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oys OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oys RCSB], [http://www.ebi.ac.uk/pdbsum/4oys PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PK3C3_HUMAN PK3C3_HUMAN]] Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.<ref>PMID:7628435</ref> <ref>PMID:14617358</ref> <ref>PMID:20208530</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Phosphatidylinositol 3-kinase]]
[[Category: Phosphatidylinositol 3-kinase]]
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[[Category: Marquette, J p.]]
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[[Category: Marquette, J p]]
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[[Category: Mathieu, M.]]
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[[Category: Mathieu, M]]
[[Category: Lipid kinase]]
[[Category: Lipid kinase]]

Revision as of 22:14, 25 December 2014

CRYSTAL STRUCTURE OF VPS34 IN COMPLEX WITH SAR405.

4oys, resolution 2.90Å

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