1j1j
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1j1j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J1J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J1J FirstGlance]. <br> | <table><tr><td colspan='2'>[[1j1j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J1J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J1J FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1key|1key]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1key|1key]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j1j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j1j RCSB], [http://www.ebi.ac.uk/pdbsum/1j1j PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j1j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j1j RCSB], [http://www.ebi.ac.uk/pdbsum/1j1j PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TSN_HUMAN TSN_HUMAN]] DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.<ref>PMID:9111049</ref> <ref>PMID:21552258</ref> Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.<ref>PMID:9111049</ref> <ref>PMID:21552258</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Hasegawa, T | + | [[Category: Hasegawa, T]] |
| - | [[Category: Kasai, M | + | [[Category: Kasai, M]] |
| - | [[Category: Kohno, T | + | [[Category: Kohno, T]] |
| - | [[Category: Matsuzaki, T | + | [[Category: Matsuzaki, T]] |
| - | [[Category: Moriyama, H | + | [[Category: Moriyama, H]] |
| - | [[Category: Sasaki, C | + | [[Category: Sasaki, C]] |
| - | [[Category: Sugio, S | + | [[Category: Sugio, S]] |
| - | [[Category: Sugiura, I | + | [[Category: Sugiura, I]] |
[[Category: Dna binding protein]] | [[Category: Dna binding protein]] | ||
[[Category: Rna binding protein]] | [[Category: Rna binding protein]] | ||
[[Category: Ssdna binding protein]] | [[Category: Ssdna binding protein]] | ||
[[Category: Testis/brain rna binding protein]] | [[Category: Testis/brain rna binding protein]] | ||
Revision as of 22:15, 25 December 2014
Crystal Structure of human Translin
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