1jnp

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1jnp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JNP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JNP FirstGlance]. <br>
<table><tr><td colspan='2'>[[1jnp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JNP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JNP FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jnp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jnp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jnp RCSB], [http://www.ebi.ac.uk/pdbsum/1jnp PDBsum]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jnp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jnp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jnp RCSB], [http://www.ebi.ac.uk/pdbsum/1jnp PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TCL1A_MOUSE TCL1A_MOUSE]] Enhances the phosphorylation and activation of AKT1 and AKT2. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Croce, C M.]]
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[[Category: Croce, C M]]
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[[Category: DuBois, G C.]]
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[[Category: DuBois, G C]]
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[[Category: Harrison, R W.]]
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[[Category: Harrison, R W]]
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[[Category: Petock, J M.]]
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[[Category: Petock, J M]]
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[[Category: Torshin, I Y.]]
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[[Category: Torshin, I Y]]
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[[Category: Wang, Y F.]]
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[[Category: Wang, Y F]]
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[[Category: Weber, I T.]]
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[[Category: Weber, I T]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
[[Category: Dimer]]
[[Category: Dimer]]
[[Category: Immune system]]
[[Category: Immune system]]

Revision as of 22:27, 25 December 2014

Crystal Structure of Murine Tcl1 at 2.5 Resolution

1jnp, resolution 2.50Å

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