2h80
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2h80]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H80 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H80 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2h80]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H80 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H80 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h80 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h80 RCSB], [http://www.ebi.ac.uk/pdbsum/2h80 PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h80 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h80 RCSB], [http://www.ebi.ac.uk/pdbsum/2h80 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/STA13_HUMAN STA13_HUMAN]] GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.<ref>PMID:14697242</ref> <ref>PMID:16217026</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Chung, S S | + | [[Category: Chung, S S]] |
| - | [[Category: Fung, K L | + | [[Category: Fung, K L]] |
| - | [[Category: Jin, D Y | + | [[Category: Jin, D Y]] |
| - | [[Category: Ko, B C | + | [[Category: Ko, B C]] |
| - | [[Category: Li, H Y | + | [[Category: Li, H Y]] |
| - | [[Category: Sun, H Z | + | [[Category: Sun, H Z]] |
[[Category: Helical bundle]] | [[Category: Helical bundle]] | ||
[[Category: Lipid binding protein]] | [[Category: Lipid binding protein]] | ||
Revision as of 22:28, 25 December 2014
NMR structures of SAM domain of Deleted in Liver Cancer 2 (DLC2)
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