1tl6

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1tl6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TL6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1tl6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TL6 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ASIA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ASIA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tl6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tl6 RCSB], [http://www.ebi.ac.uk/pdbsum/1tl6 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tl6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tl6 RCSB], [http://www.ebi.ac.uk/pdbsum/1tl6 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ASIA_BPT4 ASIA_BPT4]] Transcriptional inhibitor. Inhibits sigma 70-directed transcription by weakening its interaction with the core of the host's RNA polymerase. This allows Gp55 to successfully compete for the core enzyme. Plays an important role during the prereplicative period of phage T4 development.<ref>PMID:8021178</ref> <ref>PMID:15257291</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Enterobacteria phage t4]]
[[Category: Enterobacteria phage t4]]
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[[Category: Demeler, B.]]
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[[Category: Demeler, B]]
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[[Category: Lambert, L J.]]
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[[Category: Lambert, L J]]
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[[Category: Schirf, V.]]
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[[Category: Schirf, V]]
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[[Category: Wei, Y.]]
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[[Category: Wei, Y]]
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[[Category: Werner, M H.]]
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[[Category: Werner, M H]]
[[Category: Asia]]
[[Category: Asia]]
[[Category: T4 bacteriophage]]
[[Category: T4 bacteriophage]]
[[Category: Transcription]]
[[Category: Transcription]]

Revision as of 22:39, 25 December 2014

Solution structure of T4 bacteriphage AsiA monomer

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