3kk8
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kk8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kk8 RCSB], [http://www.ebi.ac.uk/pdbsum/3kk8 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kk8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kk8 RCSB], [http://www.ebi.ac.uk/pdbsum/3kk8 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q9U6Q0_CAEEL Q9U6Q0_CAEEL]] Role in locomotion and neuronal cell fate specification. Required for the regulation of synaptic density, egg laying, defecation, and meiotic maturation. Required for viability under chronic osmotic stress in which it acts downstream of osr-1. Regulates the synaptic trafficking of glr-1. Bidirectional modulator of neurotransmitter release with negative modulatory effects mainly mediated via slo-1 activation. May suppress the functional response to an internal pacemaker, perhaps by modulating the activity of the IP3 receptor.<ref>PMID:15166144</ref> <ref>PMID:16079277</ref> <ref>PMID:17898212</ref> <ref>PMID:17942636</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 22:42, 25 December 2014
CaMKII Substrate Complex A
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