1j48
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1j48]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_globisporus Streptomyces globisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J48 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J48 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1j48]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_globisporus Streptomyces globisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J48 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J48 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j48 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j48 RCSB], [http://www.ebi.ac.uk/pdbsum/1j48 PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j48 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j48 RCSB], [http://www.ebi.ac.uk/pdbsum/1j48 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CAGA_STRGL CAGA_STRGL]] Binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Streptomyces globisporus]] | [[Category: Streptomyces globisporus]] | ||
| - | [[Category: Bartlam, M | + | [[Category: Bartlam, M]] |
| - | [[Category: Chen, Y | + | [[Category: Chen, Y]] |
| - | [[Category: Gao, Y | + | [[Category: Gao, Y]] |
| - | [[Category: Jin, L | + | [[Category: Jin, L]] |
| - | [[Category: Li, J | + | [[Category: Li, J]] |
| - | [[Category: Liu, Y | + | [[Category: Liu, Y]] |
| - | [[Category: Rao, Z | + | [[Category: Rao, Z]] |
| - | [[Category: Shao, Y | + | [[Category: Shao, Y]] |
| - | [[Category: Tang, H | + | [[Category: Tang, H]] |
| - | [[Category: Zhen, Y | + | [[Category: Zhen, Y]] |
[[Category: Antibiotic]] | [[Category: Antibiotic]] | ||
[[Category: Dna-binding]] | [[Category: Dna-binding]] | ||
Revision as of 22:48, 25 December 2014
Crystal Structure of Apo-C1027
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Categories: Streptomyces globisporus | Bartlam, M | Chen, Y | Gao, Y | Jin, L | Li, J | Liu, Y | Rao, Z | Shao, Y | Tang, H | Zhen, Y | Antibiotic | Dna-binding
