Integrin

(Difference between revisions)

Revision as of 08:03, 30 December 2014

Structure of human integrein CD11a I domain dimer complex with Mg+2 (light green) and Cl- (dark green) ions (PDB entry 1zoo)

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Updated on 30-December-2014

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 <StructureSection load='1zoo' size='400' side='right' caption='Structure of human integrein CD11a I domain dimer complex with Mg+2 (light green) and Cl- (dark green) ions  (PDB entry [[1zoo]])' scene=''>
-'''Integrins''' (IG) are receptors which mediate the attachment between cells or to extracellular matrix.  They are involved in cellular signaling and cell cycle.  IGs contain α and β chain.  IG subunits span the cell membrane.  Both subunits bind divalent cations some of which bind the ligands which interact with IG.  Some IGs contain an insertion domain named I domain.
+'''Integrins''' (IG) are receptors which mediate the attachment between cells or to extracellular matrix.  They are involved in cellular signaling and cell cycle.  IGs contain α and β chain.  IG subunits span the cell membrane.  Both subunits bind divalent cations some of which bind the ligands which interact with IG.  Some IGs contain an insertion domain named I domain.  For more details see [[Molecular Playground/IntegrinBeta1]].
 </StructureSection>