Molecular Playground/UreE
From Proteopedia
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==Introduction== | ==Introduction== | ||
| - | <StructureSection load='3tj8' size='340' side='right' caption='UreE (PDB ID: [[ | + | <StructureSection load='3tj8' size='340' side='right' caption='UreE complex with formate and Ni+2 ion (green) (PDB ID: [[3tj8]]). ' scene=''> |
'''UreE''' is an essential metallochaeprone for ''Helicobacter pylori'' (''H.pylori''). ''H.pylori'' is a class I human pathogen that is involved in causing gastric ulcers and stomach cancers. Its two nickel dependent enzymes - Urease and NiFe-H2ase, provides it a unique ability to survive and colonize in acidic human stomach. Urease catalyzes the conversion of urea to ammonia and carbamate which neutralizes its local acidic environment. | '''UreE''' is an essential metallochaeprone for ''Helicobacter pylori'' (''H.pylori''). ''H.pylori'' is a class I human pathogen that is involved in causing gastric ulcers and stomach cancers. Its two nickel dependent enzymes - Urease and NiFe-H2ase, provides it a unique ability to survive and colonize in acidic human stomach. Urease catalyzes the conversion of urea to ammonia and carbamate which neutralizes its local acidic environment. | ||
== Function == | == Function == | ||
Revision as of 08:34, 30 December 2014
Introduction
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