4nz9

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'''Unreleased structure'''
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==Crystal Structure of FabI from S. aureus in complex with a novel benzimidazole inhibitor==
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<StructureSection load='4nz9' size='340' side='right' caption='[[4nz9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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The entry 4nz9 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4nz9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NZ9 FirstGlance]. <br>
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Authors: Mehboob, S., Johnson, M.E., Santarsiero, B.D.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1JT:1-(4-METHOXY-3-METHYLBENZYL)-5,6,7,8-TETRAHYDRO-1H-NAPHTHO[2,3-D]IMIDAZOLE'>1JT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADPH,_Re-specific) Enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.39 1.3.1.39] </span></td></tr>
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Description: Crystal Structure of FabI from S. aureus in complex with a novel benzimidazole inhibitor
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nz9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nz9 RCSB], [http://www.ebi.ac.uk/pdbsum/4nz9 PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Santarsiero, B.D]]
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__TOC__
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[[Category: Johnson, M.E]]
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</StructureSection>
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[[Category: Johnson, M E]]
[[Category: Mehboob, S]]
[[Category: Mehboob, S]]
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[[Category: Santarsiero, B D]]
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[[Category: Nadph]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Reductase]]
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[[Category: Reduction]]
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[[Category: Rossmann fold]]

Revision as of 14:50, 31 December 2014

Crystal Structure of FabI from S. aureus in complex with a novel benzimidazole inhibitor

4nz9, resolution 2.30Å

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