4q67
From Proteopedia
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| - | ''' | + | ==Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH== |
| - | + | <StructureSection load='4q67' size='340' side='right' caption='[[4q67]], [[Resolution|resolution]] 2.04Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4q67]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q67 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q67 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q6a|4q6a]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q67 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q67 RCSB], [http://www.ebi.ac.uk/pdbsum/4q67 PDBsum]</span></td></tr> |
| - | [[Category: Reeve, S | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/W7NDF6_STAAU W7NDF6_STAAU]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[PIRNR:PIRNR000194] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Dihydrofolate reductase]] | ||
| + | [[Category: Anderson, A C]] | ||
| + | [[Category: Reeve, S M]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 14:52, 31 December 2014
Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH
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