4wil
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of DCoH2 S51T== |
| - | + | <StructureSection load='4wil' size='340' side='right' caption='[[4wil]], [[Resolution|resolution]] 1.36Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4wil]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WIL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WIL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4a-hydroxytetrahydrobiopterin_dehydratase 4a-hydroxytetrahydrobiopterin dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.96 4.2.1.96] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wil OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wil RCSB], [http://www.ebi.ac.uk/pdbsum/4wil PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/PHS2_MOUSE PHS2_MOUSE]] Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 (By similarity). Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: 4a-hydroxytetrahydrobiopterin dehydratase]] | ||
| + | [[Category: Rose, R B]] | ||
[[Category: Wang, D]] | [[Category: Wang, D]] | ||
| - | [[Category: | + | [[Category: Bifunctional]] |
| + | [[Category: Coactivator]] | ||
| + | [[Category: Kinetic stability]] | ||
| + | [[Category: Lyase]] | ||
| + | [[Category: Tetrahydrobiopterin recycling]] | ||
Revision as of 14:55, 31 December 2014
Crystal structure of DCoH2 S51T
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