2g1w

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[[Image:2g1w.gif|left|200px]]<br /><applet load="2g1w" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2g1w.gif|left|200px]]
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caption="2g1w" />
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'''NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1'''<br />
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{{Structure
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|PDB= 2g1w |SIZE=350|CAPTION= <scene name='initialview01'>2g1w</scene>
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2G1W is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G1W OCA].
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2G1W is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G1W OCA].
==Reference==
==Reference==
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NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation., Nonin-Lecomte S, Felden B, Dardel F, Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16595798 16595798]
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NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation., Nonin-Lecomte S, Felden B, Dardel F, Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16595798 16595798]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Dardel, F.]]
[[Category: Dardel, F.]]
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[[Category: trans-translation]]
[[Category: trans-translation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:27:19 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:59:26 2008''

Revision as of 14:59, 20 March 2008


PDB ID 2g1w

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NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1


Overview

The transfer-messenger RNA (tmRNA) pseudoknot PK1 is essential for bacterial trans-translation, a ribosomal rescue mechanism. We report the solution structure of PK1 from Aquifex aeolicus, which despite an unprecedented small number of nucleotides and thus an unprecented compact size, displays a very high thermal stability. Several unusual structural features account for these properties and indicate that PK1 belongs to the class of ribosomal frameshift pseudoknots. This suggests a similarity between the mechanism of programmed ribosomal frameshifting and trans-translation.

About this Structure

2G1W is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation., Nonin-Lecomte S, Felden B, Dardel F, Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:16595798

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