3p8c

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3p8c]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P8C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P8C FirstGlance]. <br>
<table><tr><td colspan='2'>[[3p8c]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P8C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P8C FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYFIP1, KIAA0068 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), NCKAP1, HEM2, KIAA0587, NAP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), WASF1, KIAA0269, SCAR1, WAVE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), C3orf10, HSPC300, MDS027 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYFIP1, KIAA0068 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), NCKAP1, HEM2, KIAA0587, NAP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), WASF1, KIAA0269, SCAR1, WAVE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), C3orf10, HSPC300, MDS027 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p8c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p8c RCSB], [http://www.ebi.ac.uk/pdbsum/3p8c PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p8c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p8c RCSB], [http://www.ebi.ac.uk/pdbsum/3p8c PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/CYFP1_HUMAN CYFP1_HUMAN]] Angelman syndrome.
[[http://www.uniprot.org/uniprot/CYFP1_HUMAN CYFP1_HUMAN]] Angelman syndrome.
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Structure and control of the actin regulatory WAVE complex.,Chen Z, Borek D, Padrick SB, Gomez TS, Metlagel Z, Ismail AM, Umetani J, Billadeau DD, Otwinowski Z, Rosen MK Nature. 2010 Nov 25;468(7323):533-8. PMID:21107423<ref>PMID:21107423</ref>
Structure and control of the actin regulatory WAVE complex.,Chen Z, Borek D, Padrick SB, Gomez TS, Metlagel Z, Ismail AM, Umetani J, Billadeau DD, Otwinowski Z, Rosen MK Nature. 2010 Nov 25;468(7323):533-8. PMID:21107423<ref>PMID:21107423</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Billadeau, D D.]]
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[[Category: Billadeau, D D]]
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[[Category: Borek, D.]]
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[[Category: Borek, D]]
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[[Category: Chen, Z.]]
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[[Category: Chen, Z]]
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[[Category: Gomez, T S.]]
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[[Category: Gomez, T S]]
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[[Category: Ismail, A M.]]
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[[Category: Ismail, A M]]
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[[Category: Metlagel, Z.]]
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[[Category: Metlagel, Z]]
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[[Category: Otwinowski, Z.]]
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[[Category: Otwinowski, Z]]
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[[Category: Padrick, S B.]]
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[[Category: Padrick, S B]]
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[[Category: Rosen, M K.]]
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[[Category: Rosen, M K]]
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[[Category: Umetani, J.]]
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[[Category: Umetani, J]]
[[Category: Actin polymerization]]
[[Category: Actin polymerization]]
[[Category: Protein binding]]
[[Category: Protein binding]]

Revision as of 21:11, 3 January 2015

Structure and Control of the Actin Regulatory WAVE Complex

3p8c, resolution 2.29Å

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