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3nz7
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3nz7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NZ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NZ7 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3nz7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NZ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NZ7 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SNS:3,6-BIS(3-(3-(S)-FLUOROPYRROLINDINO)PROPIONAMIDO)ACRIDINE'>SNS</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=SNS:3,6-BIS(3-(3-(S)-FLUOROPYRROLINDINO)PROPIONAMIDO)ACRIDINE'>SNS</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jpq|1jpq]], [[1jrn|1jrn]], [[1l1h|1l1h]], [[3ce5|3ce5]], [[3em2|3em2]], [[3eqw|3eqw]], [[3eru|3eru]], [[3es0|3es0]], [[3et8|3et8]], [[3eui|3eui]], [[3eum|3eum]], [[3nyp|3nyp]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jpq|1jpq]], [[1jrn|1jrn]], [[1l1h|1l1h]], [[3ce5|3ce5]], [[3em2|3em2]], [[3eqw|3eqw]], [[3eru|3eru]], [[3es0|3es0]], [[3et8|3et8]], [[3eui|3eui]], [[3eum|3eum]], [[3nyp|3nyp]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nz7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nz7 RCSB], [http://www.ebi.ac.uk/pdbsum/3nz7 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nz7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nz7 RCSB], [http://www.ebi.ac.uk/pdbsum/3nz7 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Fluorine in medicinal chemistry: beta-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNA.,Campbell NH, Smith DL, Reszka AP, Neidle S, O'Hagan D Org Biomol Chem. 2011 Mar 7;9(5):1328-31. Epub 2011 Jan 10. PMID:21221451<ref>PMID:21221451</ref> | Fluorine in medicinal chemistry: beta-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNA.,Campbell NH, Smith DL, Reszka AP, Neidle S, O'Hagan D Org Biomol Chem. 2011 Mar 7;9(5):1328-31. Epub 2011 Jan 10. PMID:21221451<ref>PMID:21221451</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Campbell, N H | + | [[Category: Campbell, N H]] |
| - | [[Category: Neidle, S | + | [[Category: Neidle, S]] |
[[Category: Acridine]] | [[Category: Acridine]] | ||
[[Category: Anti-parallel]] | [[Category: Anti-parallel]] | ||
Revision as of 21:20, 3 January 2015
A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine ligand containing bis-3-fluoropyrrolidine end side chains
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Categories: Campbell, N H | Neidle, S | Acridine | Anti-parallel | Bimolecular | Bsu-6039 | Bsu6039 | Dna | Fluorination | G-quadruplex | Macromolecule | Oxtyricha nova | Quadruplex | Telomere
