2g5o
From Proteopedia
(Difference between revisions)
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- | [[Image:2g5o.gif|left|200px]] | + | [[Image:2g5o.gif|left|200px]] |
- | + | ||
- | '''Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide''' | + | {{Structure |
+ | |PDB= 2g5o |SIZE=350|CAPTION= <scene name='initialview01'>2g5o</scene>, resolution 2.30Å | ||
+ | |SITE= | ||
+ | |LIGAND= <scene name='pdbligand=DRQ:(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL'>DRQ</scene> | ||
+ | |ACTIVITY= | ||
+ | |GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
+ | }} | ||
+ | |||
+ | '''Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide''' | ||
+ | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
- | 2G5O is a [ | + | 2G5O is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G5O OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: lbd]] | [[Category: lbd]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:00:44 2008'' |
Revision as of 15:00, 20 March 2008
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, resolution 2.30Å | |||||||
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Ligands: | |||||||
Gene: | ESR1, ESR, NR3A1 (Homo sapiens) | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide
Disease
Known diseases associated with this structure: Atherosclerosis, susceptibility to OMIM:[133430], Breast cancer OMIM:[133430], Estrogen resistance OMIM:[133430], HDL response to hormone replacement, augmented OMIM:[133430], Migraine, susceptibility to OMIM:[133430], Myocardial infarction, susceptibility to OMIM:[133430]
About this Structure
2G5O is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 17:00:44 2008