2y0c

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<StructureSection load='2y0c' size='340' side='right' caption='[[2y0c]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='2y0c' size='340' side='right' caption='[[2y0c]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2y0c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_cepacia Burkholderia cepacia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0C OCA]. <br>
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<table><tr><td colspan='2'>[[2y0c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_cepacia Burkholderia cepacia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y0C FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=UGA:URIDINE-5-DIPHOSPHATE-GLUCURONIC+ACID'>UGA</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=UGA:URIDINE-5-DIPHOSPHATE-GLUCURONIC+ACID'>UGA</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y0e|2y0e]], [[2y0d|2y0d]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y0e|2y0e]], [[2y0d|2y0d]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-glucose_6-dehydrogenase UDP-glucose 6-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.22 1.1.1.22] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y0c RCSB], [http://www.ebi.ac.uk/pdbsum/2y0c PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y0c RCSB], [http://www.ebi.ac.uk/pdbsum/2y0c PDBsum]</span></td></tr>
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<table>
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</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structure of Burkholderia cepacia UDP-Glucose Dehydrogenase (UGD) BceC and Role of Tyr10 in Final Hydrolysis of UGD Thioester Intermediate.,Rocha J, Popescu AO, Borges P, Mil-Homens D, Moreira LM, Sa-Correia I, Fialho AM, Frazao C J Bacteriol. 2011 Aug;193(15):3978-87. Epub 2011 May 20. PMID:21602353<ref>PMID:21602353</ref>
Structure of Burkholderia cepacia UDP-Glucose Dehydrogenase (UGD) BceC and Role of Tyr10 in Final Hydrolysis of UGD Thioester Intermediate.,Rocha J, Popescu AO, Borges P, Mil-Homens D, Moreira LM, Sa-Correia I, Fialho AM, Frazao C J Bacteriol. 2011 Aug;193(15):3978-87. Epub 2011 May 20. PMID:21602353<ref>PMID:21602353</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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[[Category: Burkholderia cepacia]]
[[Category: Burkholderia cepacia]]
[[Category: UDP-glucose 6-dehydrogenase]]
[[Category: UDP-glucose 6-dehydrogenase]]
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[[Category: Borges, P.]]
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[[Category: Borges, P]]
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[[Category: Fialho, A M.]]
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[[Category: Fialho, A M]]
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[[Category: Frazao, C.]]
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[[Category: Frazao, C]]
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[[Category: Mil-Homens, D.]]
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[[Category: Mil-Homens, D]]
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[[Category: Popescu, A O.]]
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[[Category: Popescu, A O]]
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[[Category: Rocha, J.]]
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[[Category: Rocha, J]]
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[[Category: Sa-Correia, I.]]
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[[Category: Sa-Correia, I]]
[[Category: Carbohydrate synthesis]]
[[Category: Carbohydrate synthesis]]
[[Category: Cystic fibrosis]]
[[Category: Cystic fibrosis]]
[[Category: Exopolysaccharide]]
[[Category: Exopolysaccharide]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 21:37, 3 January 2015

BCEC MUTATION Y10S

2y0c, resolution 1.75Å

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